Normal semen analysis? Still not pregnant?

Just because you got a “Normal” result on your Semen Analysis test doesn’t mean the sperm are capable of doing their job: starting a pregnancy.

Instead, SpermQT™ helps predict pregnancy outcomes by measuring sperm function, not just sperm count, giving you clearer information for decisions like whether to continue with IUI (Intrauterine Insemination) or move to IVF (In vitro fertilization).¹·²·³

“Why can’t we get pregnant?”

For better or worse, a Semen Analysis test only determines the number of sperm and if they can swim (as explained here).

But often, that knowledge is not enough, especially since our clinical research shows that 15% to 22% of couples with a “Normal” Semen Analysis test result are still infertile.¹·³ (See this summary of our clinical test results)

That’s why we invented SpermQT, a super quick and easy-to-use test designed to determine if your sperm can actually do what they’re supposed to do: Swim,
• Find the egg,
• Bind to the egg,
• Penetrate the egg, and
• Fertilize the egg.

And SpermQT is both highly accurate and inexpensive.

See how SpermQT works

In their own words

SpermQT has transformed the fertility journey for couples and doctors by providing clear insights and solutions that have made a real difference.

Unexplained Infertility

3 Failed IUIs

TTC for 2+ Years

SpermQT was helpful, especially for my husband who had done two sperm tests prior and both came back normal.

Then our SpermQT result came back Abnormal, so it helped us move forward.

Chelsea

I wish we did SpermQT before we started IUI.

It wasn’t so much of the cost of the IUIs but more of the time, and there were a lot of emotions involved.

Zachary

SpermQT is something that gave us a lot of peace because we had a lot of questions that couldn’t be answered.

It just gave us an enormous sense of peace.

Evelyn

Women are frequently frustrated that they have to submit to a battery of fertility tests, while their partners just do a semen analysis that only measures rudimentary sperm values.

SpermQT gives us a powerful new tool in our toolbox.

Dr. Kaylen Silverberg

A semen analysis is like a photograph of sperm, what we’re missing is functional testing of sperm.

I use SpermQT as a functional test of sperm’s ability to actually result in a pregnancy.

Dr. Puneet Masson

I order SpermQT for 60% of my patients.

The test allows us to know if sperm can do its job to find, bind, penetrate, and fertilize an egg.

Dr. Susan Hudson

Order Now

We work with providers and patients at all stages of the fertility journey

PROVIDERS >

Start using SpermQT within your practice to guide treatment planning.

PATIENTS >

Learn more about how SpermQT can impact your path to pregnancy.

Convenient and Non-invasive

Patients can choose to collect their sample in the doctor’s office or at home with an easy-to-use kit. Samples are shipped off to the lab for analysis and results are delivered within 2-weeks – it’s as easy as that!

Our Products

Personalize the Path to Pregnancy

SpermQT provides insights that are different from the standard semen analysis and DNA Fragmentation, guiding you to make more informed decisions on your fertility journey.

Science

We’re on a mission

We believe the path to pregnancy is a shared journey that deserves the best that science has to offer. Couples who acknowledge the unique biology of both the egg and the sperm can make more informed plans when trying to conceive. Path Fertility is on a mission to raise the standard of care in reproductive health, and in turn, help both patients and providers gain a better understanding of fertility potential.

Path Fertility: RAISE THE STANDARD.

References

Miller, Ryan H et al. “Epigenetic determinants of reproductive potential augment the predictive ability of the semen analysis” Fertility and sterility science vol. 4,4 (2023): 279-285. doi: 10.1016/j.xfss.2023.09.001
Aston, Kenneth I et al. “Aberrant sperm DNA methylation predicts male fertility status and embryo quality.” Fertility and sterility vol. 104,6 (2015): 1388-97.e1-5. doi:10.1016/j.fertnstert.2015.08.019; Jenkins TG, Aston KI, Meyer TD, et al. Decreased fecundity and sperm DNA methylation patterns. Fertil Steril. 2016;105(1):51-7.e73. doi:10.1016/j.fertnstert.2015.09.013
Brogaard, K., Hudson, S., Bedient, C. et al. Epigenetic sperm quality testing for predicting fertility treatment success: a real-world and multi-site analysis. J Assist Reprod Genet (2026). https://doi.org/10.1007/s10815-025-03791-0. SPOT clinical trial data on file internally. NCT05966883