Introducing Path SpermQT™

Path SpermQT is an epigenetic sperm quality test that can predict poor fertility outcomes that are not identified with standard semen analysis alone. 

80% of men with a Poor SpermQT result had normal sperm concentration and total motile count.¹

A new way to assess sperm quality could offer earlier, more directed treatment options for fertility. 

Path SpermQT combined with a standard semen analysis can provide valuable new information about sperm quality to help guide treatment options and increase the chance for pregnancy success.


White Paper
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Path SpermQT at a Glance

  • Validated in over 2,000 semen samples¹‚²

  • Run in a CAP accredited and CLIA certified laboratory³

  • Catagorizes sperm quality as Excellent, Normal or Poor

  • Studies show a statistically significant increase in pregnancy rates using IVF over IUI in men with a Poor Path SpermQT result¹

  • Path SpermQT is the only test that has discovered how the molecular analysis of sperm can identify men with normal semen parameters that most likely need IVF to achieve pregnancy¹


How it works 

We deliver a kit directly to your patient’s home for a discreet collection process. We deliver results to you. 

This is a physician ordered test.

Submit a completed requisition via fax or email.

Fax: 385-800-8998

This test is convenient for your patient.

Our kit ships directly to your patient’s home, with a pre-paid return shipping label to our CAP accredited and CLIA certified lab facility.

We handle the shipping and lab analysis.

Prepaid shipping with USPS for convenience with no need for temperature control.

We’re analyzing the DNA, which is protected in the head of the sperm.

Get the epigenetic analysis in two weeks.

Once your patient sends their semen specimen to the lab, the analysis is completed within 2 weeks.

We send the Path SpermQT report to you.

Download Requisition

Looking for a sample report?
Need more information? 

We’d love to connect.


  1. Path SpermQT White Paper;  Jenkins, Tim et al. “The impact of zinc and folic acid supplementation on sperm DNA methylation: results from the folic acid and zinc supplementation randomized clinical trial (FAZST).” Fertility and sterility vol. 117,1 (2022): 75-85. doi:10.1016/j.fertnstert.2021.09.009
  2. Aston, Kenneth I et al. “Aberrant sperm DNA methylation predicts male fertility status and embryo quality.” Fertility and sterility vol. 104,6 (2015): 1388-97.e1-5. doi:10.1016/j.fertnstert.2015.08.019; Jenkins TG, Aston KI, Meyer TD, et al. Decreased fecundity and sperm DNA methylation patterns. Fertil Steril. 2016;105(1):51-7.e73. doi:10.1016/j.fertnstert.2015.09.013
  3. CAP/CLIA validation documents on file internally 
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